WASHINGTON — The Drug Enforcement Administration said Friday it will no longer accept labels for painkillers unless they are in compliance with federal law.

The announcement came after a series of new rules by the FDA that are intended to ensure that prescription painkillers and other drugs can be used in a responsible manner.

The FDA said in a statement that it is reviewing how it handles labels that are in violation of the Controlled Substances Act and other federal law enforcement and health care policies.

It’s important that consumers know the drugs they are taking are safe, the agency said.

It said it would “review all the labels of prescription drugs to ensure they are consistent with applicable federal, state, and local laws and regulations and the information contained therein.”FDA officials said they have received numerous complaints from consumers about prescription painkiller labels.

The agency has also received complaints from some pharmacies.